Saracens full-back Max Malins has had surgery to repair a broken foot, ruling him out for three months.
The 23-year-old former England Under-20 international suffered the injury in Sarries’ 14-7 defeat at Premiership leaders Exeter on 29 December.
He will now begin a rehabilitation programme following Monday’s successful operation but is expected to be out of action until April.
Saracens are bottom of the Premiership table on -7 points.
The reigning champions were docked 35 points and fined £5.36m in November for breaching salary cap regulations.
England head coach Eddie Jones fears some Saracens players could skip the Six Nations campaign to help their club avoid relegation after a 35-point deduction for salary cap breaches.
The deduction leaves the Premiership champions bottom of the table. They have also been fined £5.36m.
Sarries supplied six of the team who started for England in the 32-12 defeat by South Africa in the World Cup final.
“It could have a significant impact,” Jones told BBC Sport.
“It’s something we need to weigh up and look at very carefully.”
Saracens have decided not to appeal against the punishments imposed upon them for infringements over the past three seasons so go from third place to bottom of the Premiership on -22 points, 26 behind second-bottom Leicester.
Jones selected six of their players for the final in Yokohama, led by captain Owen Farrell. The others were Mako and Billy Vunipola, hooker Jamie George, second row Maro Itoje and full-back Elliott Daly, who is yet to play for the club after his summer move from Wasps.
“Obviously there may be some dislocation between Saracens players and the rest of the clubs,” said Jones, who was Saracens’ director of rugby in 2008-09. “That’s a reality.
“So we may have to work to mend those relationships a bit harder, and there might be some Saracens players who feel like they’ve got to play for their club instead of their country, to make sure they don’t go down. So we’ll weigh all those up as they come about.”
Former Sarries and England scrum-half Kyran Bracken believed Jones was correct to be concerned.
“Country comes first traditionally, but the players will feel a sense of loyalty to the club having won so much with them,” the 47-year-old told the BBC News Channel.
“The thought of potentially leaving comrades in the lurch and leaving young guys to it… some will decide to concentrate on Saracens.”
‘I didn’t realise how strong the class structure was’
Ensuring any issues between Saracens players and the rest of the squad do not do any damage is the latest challenge Jones must face as England coach.
Earlier he told BBC Radio 5 Live that the biggest hurdle he faced when he first took the job in January 2016 was getting to grips with the cultural differences within the group.
“I didn’t realise the how strong the class structure was in England, and how that affects the relationships between the players,” the Australian said.
“When you look at the England team from the outside it looks like a very homogeneous group but in fact it’s very diverse and there probably hasn’t been enough understanding of the diversity of the group.
“We spent a lot of time in our World Cup prep making sure we understood the value of diversity.”
A report this year revealed that 37% of male British rugby union internationals came from fee-paying schools.
Jones, who hails from a working class suburb of Sydney, was asked whether the difference came down to the stereotypical rugby divide of “posh public schoolboys and state school kids”.
“Something like that, yeah,” he said.
“If you’ve got a group of people in here now and you’ve got five Japanese people, five Australians and five South Africans, they’ll tend to congregate together and that’s OK if they’re not playing as a team.
“But if those 15 are playing as a team then you want that to be completely mixed, and they’re the subtle things I was reasonably slow to pick up on.”
|Saracens (23) 44|
|Tries: Maitland, Spencer, Williams, Tompkins 3 Cons: Farrell 4 Pens: Farrell 2|
|Gloucester (7) 19|
|Tries: Morgan, Dreyer, Ludlow Cons: Twelvetrees 2 Pens:|
Nick Tompkins’ second-half hat-trick helped Saracens cruise past Gloucester 44-19 and keep up their hopes of a second domestic and European double.
Ben Morgan’s second-minute try was cancelled out by scores from Sean Maitland, Ben Spencer and Liam Williams as Owen Farrell kicked eight points in an engrossing first half.
Replacement Tompkins’ treble came in the first 16 minutes after the break.
Ruan Dreyer and Lewis Ludlow got consolation tries for Gloucester.
Victory set up a final date at Twickenham next Saturday against old foes Exeter, who Saracens beat to lift the Premiership crown in both 2016 and 2018.
Gloucester looked like they could upset the form book as Morgan went over after a superb six-pass move that included a lovely reverse ball by Mark Atkinson to open up a hole in the Saracens defence.
But Mark McCall’s side showed why they are Europe’s best as they strangled Gloucester’s ambitions and pressurised them with high balls and front-foot defence.
They hit back within two minutes as Maitland gathered Farrell’s grubber kick, after Williams acrobatically kept the ball alive from the kick-off, before Spencer crossed after a brilliant 40-metre break and dummy by Maro Itoje.
Gloucester’s first half was summed up by two moments in the final 10 minutes – first Charlie Sharples’ pass after a lovely backs move was intercepted by Alex Goode when the Cherry and Whites had an overlap, and then Alex Lozowski snaffled a high kick and fed Sarries’ Wales and British and Irish Lions star Williams, who coasted into the corner.
First-half replacement Tompkins’ first score was a 40-metre dash a minute after the restart, while his second came at the end of some slick inter-passing from his team-mates and his third was from a metre out after Goode was held up on the Gloucester line.
Front-row replacement Dreyer got one try back after a lovely dummy opened up a gap under the posts while Ludlow ran in from distance following a cute Billy Twelvetrees offload.
But Saracens were not troubled as they made a fifth Premiership final in six years.
Farrell wins battle with Cipriani
The pre-match hype centred on the contest between arguably the best two fly-halves in the country as double Player of the Year Cipriani faced up against England’s first-choice Owen Farrell.
Saracens’ defence did not allow Gloucester the opportunities to get the ball into Cipriani’s hands and show his talent, while Farrell was key to his side’s first try.
Although the Saracens man did miss a number of kickable penalties, barring injury you would expect Farrell to be the one of the first men on the plane to Japan for the World Cup.
Whether Cipriani’s performance has persuaded Eddie Jones that he should join him is still in the balance.
Saracens sweat over Barritt
Saracens’ only concern from the victory was seeing skipper Brad Barritt limp off after 27 minutes.
The former England centre appeared to have a hamstring problem and would seem a major doubt for next week’s showpiece at Twickenham.
However, his replacement Tompkins proved a more than able deputy as his tries snuffed out any hope of a Cherry and Whites comeback.
“It’s devastating to lose Brad and it’s very unlikely he’ll be able to play in the final,” said Saracens director of rugby Mark McCall. “Given what he’s given the team this year, that feels very sad.
“Nick has had a phenomenal game. He’s been involved in every Premiership and European game this season. He’s been one of the players who has risen this year.”
Saracens director of rugby Mark McCall:
“I feel quite funny because the scoreline does them [Gloucester] a disservice. We need to be better against whoever we play at Twickenham next weekend.
“It’s almost perfect because we’ve won comfortably and scored some good tries, but still have a frustrated changing room.
“If we want to get the result we want [in the final], then we need to be better. The players understand that.
“For 10 minutes before half-time and 10 minutes after, we took advantage of some crucial turnovers. Our ability to recover the ball from kicks was outstanding.
“But there were other parts of the game we weren’t too happy with, so there are enough things for us to fix.”
Saracens: Goode; Williams, Lozowski, Barrett (capt), Maitland; Farrell, Spencer; Barrington, George, Koch, Skelton, Kruis, Itoje, Wray, B Vunipola.
Replacements: Gray, Adams-Hale, Judge, Isiekwe, Rhodes, Wigglesworth, Tompkins, Strettle.
Gloucester: Woodward; Sharples, Twelvetrees, Atkinson, Marshall; Cipriani, Heinz (capt); Hohneck, Marais, Balmain, Slater, Mostert, Ackermann, Kriel, Morgan.
Replacements: Sherry, Rapava Ruskin, Dreyer, Savage, Ludlow, Polledri, Vellacott, Purdy.
Referee: Luke Pearce.